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This may occur because prostaglandins play a role in the regulation of blood pressure.
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Although the idea of these topical formulations was to reduce the risk of ulcers and gastrointestinal Ibuprofen brand Buy, this has not yet been proven definitively, though the medications do cause less stomach upset. And since the topicals result in reduced levels of the NSAID medication in the body, they should theoretically pose a reduced risk of heart attack and stroke, but studies are needed to confirm this.
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